What we do?

Biosensors

Functionalization and biofunctionalization of surfaces, identyfication of parameters, advanced sensitivity measurements and surface specifity.

Biofunctionalization

Optical sensors, especially fiber optic sensors, make a universal platform for the implementation of biological research. They allow for, e.g., a Label-free and  selective detection of a wide range of biological materials in solutions, including DNA, proteins, viruses and bacteria, all done quickly and with high measurement reliability. Directly after fabrication, the optical fiber structures can measure temperature, stress and refractive index. In order to achieve selectivity for a specific biological analyte, biofunctionalization is necessary, during which the sensor surface is subjected to a series of processes of binding and activating chemical and biological layers. The biofunctionalisation processes we use have been developed and improved during almost 10 years of cooperation with the team of the Institute of Physical Chemistry PAN in Warsaw, Institute of Immunology and Experimental Therapy PAN in Wrocław and other scientific and business partners. Our work resulted in the attachment of toxins, proteins, DNA, viruses and living cells, including bacterial ones, onto the sensors surfaces.

Electrochemistry

One of the biggest advantages of using optical fiber structures in biosensors is their chemical resistance and a very limited possibility of electromagnetic interference in the measurement. This feature allows the creation of systems for two-domain measurements , in which one channel is providing information about the analyte as an optical signal, and the other is an electrochemical signal. In such a system, it is possible to extend the measurement range and simultaneous verification of the obtained measurement result in both domains, which significantly increases its reliability while saving time and the analyte.

Detection parameters

Depending on the type of sensor, the detection limit we can achieve reach even 6 attomoles in a volume of 10 pL.